Supplement
5-Hydroxytryptophan (5-HTP)
A serotonin-precursor amino acid sometimes used to support mood.
📊 How it ranks (our editor score) — 56/100Tap to see the breakdown
🌱 What it is
5-HTP is a compound the body makes from tryptophan and converts into serotonin; it is sold as a standalone supplement.
✨ Why it's good for you
- May gently support mood
- Precursor the body can use to make serotonin
- Available without a prescription
🥄 How to use it
Typically taken as 50–100 mg in the evening; some people take it earlier in the day divided into smaller doses. Talk with a doctor before starting, especially if you're already taking an antidepressant, your depression is moderate to severe, or you have thoughts of self-harm, and start low and reassess after a couple of weeks.
How much: 50–100 mg daily, generally taken in the evening; do not exceed label directions.
Why it works: 5-HTP is a direct precursor to serotonin, a brain chemical involved in mood regulation, so raising 5-HTP levels may modestly raise serotonin.
⚠️ Cautions
- Never combine with SSRIs, SNRIs, MAOIs, or other serotonergic medications — the combination can cause serotonin syndrome, a medical emergency.
- Avoid in pregnancy and breastfeeding.
- Discontinue and seek care if you develop agitation, rapid heartbeat, sweating, or confusion.
📚 What others say
- Natural Remedies Encyclopedia (7th ed.)
🕊️ A word of encouragement
Your body was wonderfully made to heal — give it rest, good food, and a little patience, and trust the One who designed it.
💬 Ask Remy about 5-Hydroxytryptophan (5-HTP)
📚 Resource confidence
Based on mentions in health references
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